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Maximum Dose: A maximum of 450 mg per day can be considered for patients who show no clinical improvement after several weeks of treatment at 300 mg per day.
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Hepatic Impairment: In patients with moderate to severe hepatic impairment, the maximum dose is 75 mg per day.
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Switching from MAOI Antidepressants: Allow at least 14 days between discontinuation of an MAOI and initiation of Wellbutrin.
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Uses:
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Tadalafil, also known by its generic name tadalafil, is a medication that relaxes muscles of the blood vessels and increases blood flow to particular areas of the body. Here are some important points about tadalafil:

Uses:
Erectile Dysfunction (Impotence): Tadalafil, marketed under the brand name , is commonly used to treat erectile dysfunction. It helps improve blood flow to the penis, facilitating erections during sexual stimulation.
Benign Prostatic Hypertrophy (Enlarged Prostate): Tadalafil is also used to manage symptoms related to an enlarged prostate (benign prostatic hypertrophy).
Pulmonary Arterial Hypertension: Another brand of tadalafil, called Adcirca, is used to treat pulmonary arterial hypertension and enhance exercise capacity in both men and women.
Warnings and Precautions:
Nitrate Medications: Do not take tadalafil if you are using a nitrate drug for chest pain or heart problems (e.g., nitroglycerin, isosorbide dinitrate, isosorbide mononitrate) or recreational drugs like “poppers.” Combining tadalafil with nitrates can cause a sudden and serious drop in blood pressure.
Other Medications: Inform your doctor about all your current medications, especially if you are taking riociguat (Adempas).
Priapism: Seek medical attention if your erection is painful or lasts longer than 4 hours (a condition called priapism). Prolonged erections can damage the penis.
Vision Loss: Stop using tadalafil and seek emergency medical help if you experience sudden vision loss.
Safety Considerations:
Avoid tadalafil if you are allergic to it.
Certain medical conditions (e.g., heart disease, stroke, high or low blood pressure, liver or kidney disease, vision loss) may affect tadalafil’s safety.
Sudden vision loss has occurred in a small number of people taking medicines like tadalafil.
Remember to follow your doctor’s instructions and report any unusual symptoms. Tadalafil can be effective, but safety precautions are essential. ?

For more detailed information, you can refer to 1.